Investigating natural compounds to lower high blood pressure
Official title: Antihypertensive Effect of Food-Origin Isothiocyanate Soluble Epoxide Hydrolase Inhibitors
Funded at Pacific University · NIH-10914842 · Data updated 2026-11-12
This study is looking at how natural compounds found in some foods might help lower blood pressure and improve heart health, and it's aimed at finding new ways to manage high blood pressure for people like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pacific University NIH-funded |
| Lab location | 1 site (Forest Grove, United States) |
| Project start | September 20, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $122,335 |
| NIH project number | 5R16GM145589-03 |
| Project ID | NIH-10914842 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are experiencing hypertension or are at risk for developing high blood pressure.
✕Less likely to help
Patients who do not have hypertension or related cardiovascular conditions may not benefit from this research.
What this research studies
This research focuses on the antihypertensive effects of isothiocyanates, which are natural compounds found in certain foods. The study aims to understand how these compounds can inhibit a specific enzyme related to blood pressure regulation. By using animal models, researchers will assess the effectiveness of these compounds in preventing high blood pressure and improving cardiovascular health. If successful, this research could lead to new dietary recommendations or treatments for managing hypertension in humans.
Why it matters
Potential benefit: If successful, this research could provide new, natural treatment options for individuals struggling with high blood pressure.
How similar studies have gone: Previous research has shown promising results with natural compounds in managing hypertension, suggesting potential for success in this approach.
Where this research is happening
-
Pacific University
Forest Grove, United States Active
Researchers
- Principal investigator: Elbarbry, Fawzy — Pacific University
- Study coordinator: Elbarbry, Fawzy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.