Investigating muscle loss and diabetes in postmenopausal women
Official title: MASS: Muscle and disease in postmenopausal women
Funded at State University of New York at Buffalo · NIH-11097339 · Data updated 2026-11-12
This study is looking at how diabetes and blood sugar issues affect muscle loss in postmenopausal women, and it aims to find ways to help prevent problems like falls and fractures, all while making it easy for participants to take part from home.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Buffalo NIH-funded |
| Lab location | 1 site (Amherst, United States) |
| Project start | September 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $568,073 |
| NIH project number | 5R01AG078249-03 |
| Project ID | NIH-11097339 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are postmenopausal women, particularly those experiencing issues related to muscle mass and diabetes.
✕Less likely to help
Patients who are not postmenopausal or do not have concerns related to muscle mass or diabetes may not benefit from this research.
What this research studies
This research focuses on understanding how diabetes and insulin-glucose imbalances contribute to muscle loss in postmenopausal women. By examining a large group of women over time, the study aims to identify modifiable risk factors that lead to functional impairments, such as falls and fractures. Participants will use a convenient at-home method for collecting samples, allowing for a comprehensive analysis of muscle mass changes and metabolic health. The study will also explore how these factors may differ across various racial and ethnic groups.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing muscle loss and related health issues in older women.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between diabetes and muscle loss, making this study a continuation of that work.
Where this research is happening
-
State University of New York at Buffalo
Amherst, United States Active
Researchers
- Principal investigator: Wactawski-Wende, Jean — State University of New York at Buffalo
- Study coordinator: Wactawski-Wende, Jean
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.