Investigating MRI lesions as indicators of nerve damage in Multiple Sclerosis
MRI Paramagnetic Rim Lesions as Biomarkers and Agents of Neurodegeneration in Multiple Sclerosis
This study is looking at certain brain changes seen in MRI scans of people with Multiple Sclerosis to see how they relate to the disease's progression and treatment, with the hope of improving how we diagnose and treat MS.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project ID | NIH-11065473 on NIH RePORTER |
What this research studies
This research focuses on understanding specific MRI lesions known as paramagnetic rim lesions (PRLs) in patients with Multiple Sclerosis (MS). By using advanced MRI techniques, the study aims to identify these lesions and explore their relationship with neurodegeneration and inflammation in the brain. The research will analyze data from a cohort of MS patients to determine how these lesions correlate with disease progression and response to treatment. Ultimately, the goal is to enhance diagnostic capabilities and treatment strategies for MS patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Multiple Sclerosis who have experienced acute inflammatory episodes.
Not a fit: Patients with other neurological disorders or those who do not have a diagnosis of Multiple Sclerosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment options for patients with Multiple Sclerosis.
How similar studies have performed: Previous research has shown promise in using MRI to identify biomarkers in neurodegenerative diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Worcester, United States
- Univ of Massachusetts Med Sch Worcester — Worcester, United States (Active)
Researchers
- Principal investigator: Hemond, Christopher C. — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Hemond, Christopher C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.