Investigating metabolic changes in ovarian cancer
Deep Ovarian Cancer Metabolomics
This study is looking at how ovarian cancer affects the body's metabolism, using mice to find changes that could help doctors detect the disease earlier and improve treatment for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10979871 on NIH RePORTER |
What this research studies
This research focuses on understanding the metabolic changes associated with ovarian cancer, particularly high-grade serous ovarian cancer. By studying mouse models, the team aims to identify specific metabolic alterations in serum and ovarian tissues that could serve as biomarkers for early detection. The research seeks to develop effective screening strategies that could improve early diagnosis and treatment outcomes for patients. The findings may lead to a better understanding of how ovarian cancer develops and progresses, potentially informing future therapeutic approaches.
Who could benefit from this research
Good fit: Ideal candidates for this research include women at high risk for ovarian cancer, particularly those with BRCA1/2 mutations or a family history of the disease.
Not a fit: Patients with advanced-stage ovarian cancer or those without a genetic predisposition to the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new biomarkers for early detection of ovarian cancer, significantly improving survival rates.
How similar studies have performed: Previous research has shown promise in identifying metabolic biomarkers for cancer detection, suggesting that this approach could yield valuable insights.
Where this research is happening
Atlanta, United States
- Georgia Institute of Technology — Atlanta, United States (Active)
Researchers
- Principal investigator: Fernandez, Facundo Martin — Georgia Institute of Technology
- Study coordinator: Fernandez, Facundo Martin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.