Investigating metabolic changes in neurological disorders
Official title: CNS-Met Metabolomics Core
Funded at University of Kentucky · NIH-11077856 · Data updated 2026-11-12
This study is looking at how problems with metabolism in the brain might be linked to conditions like Alzheimer's and brain injuries, and it’s designed to help researchers better understand these issues so they can find new ways to help people with these neurological disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project start | May 15, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $293,035 |
| NIH project number | 5P20GM148326-03 |
| Project ID | NIH-11077856 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease, traumatic brain injury, or other related neurological conditions.
✕Less likely to help
Patients with neurological disorders not related to metabolic changes may not receive benefit from this research.
What this research studies
This research focuses on understanding the metabolic defects associated with neurological disorders and central nervous system injuries, such as Alzheimer's disease and traumatic brain injury. By utilizing modern metabolomics techniques, the project aims to analyze hundreds of metabolites from brain samples, which can provide insights into bioenergetics, neurotransmitter production, and neuroinflammation. The CNS-Met Metabolomics Core will support researchers by offering expertise, training, and resources to enhance their studies on brain metabolism and its implications for various neurological conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with neurological disorders.
How similar studies have gone: Previous research has shown promising results using metabolomics in understanding neurological disorders, indicating that this approach has potential for success.
Where this research is happening
-
University of Kentucky
Lexington, United States Active
Researchers
- Principal investigator: Sullivan, Patrick G — University of Kentucky
- Study coordinator: Sullivan, Patrick G
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.