Investigating memory performance in older adults who age well
Clinical/Imaging Core
This study is looking at a special group of older adults called 'SuperAgers' who have great memory skills even as they age, and we're hoping to learn what helps them stay sharp so we can help others do the same.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11082259 on NIH RePORTER |
What this research studies
This research focuses on understanding a unique group of elderly individuals, referred to as 'SuperAgers', who maintain exceptional memory abilities despite their age. By studying participants aged 80 and older, the project aims to identify factors that contribute to their cognitive resilience against Alzheimer's disease and other age-related memory decline. The study will involve comprehensive assessments, including health evaluations, lifestyle factors, neurocognitive tests, MR imaging, and blood samples, to gather data that could inform future interventions. Participants will be recruited from diverse backgrounds across the United States and Canada to ensure a representative sample.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals aged 80 and older who exhibit strong memory performance and may be classified as SuperAgers.
Not a fit: Patients who are younger than 80 or those already diagnosed with significant cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and strategies for preventing or delaying Alzheimer's disease and cognitive decline in the elderly.
How similar studies have performed: Previous research on cognitive resilience in aging populations has shown promising results, suggesting that understanding SuperAgers could lead to significant advancements in Alzheimer's prevention strategies.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Weintraub, Sandra — University of Chicago
- Study coordinator: Weintraub, Sandra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.