Investigating memory decline in aging adults with autism

The Aging Autistic Brain: Multi-modal imaging to predict accelerated memory decline

NIH-funded research Arizona State University-Tempe Campus · NIH-10996183

This study is looking at how getting older affects memory in adults with autism, using brain scans to see how their memory and brain activity change over time compared to those without autism, so we can better understand the memory challenges they might face as they age.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionArizona State University-Tempe Campus NIH-funded
Lab location1 site (Tempe, United States)
Project IDNIH-10996183 on NIH RePORTER

What this research studies

This research focuses on understanding how aging affects memory in adults with autism spectrum disorder (ASD). It utilizes advanced imaging techniques, including functional MRI and diffusion tensor imaging, to observe changes in brain structure and function over time. By comparing memory performance and brain activity in middle-aged and older adults with ASD to those without, the study aims to identify early indicators of accelerated memory decline. Participants will undergo various memory tasks while their brain activity is monitored, providing insights into the unique challenges faced by this population as they age.

Who could benefit from this research

Good fit: Ideal candidates for participation include middle-aged and older adults diagnosed with autism spectrum disorder.

Not a fit: Patients who are not diagnosed with autism spectrum disorder or are younger than middle age may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved early detection and intervention strategies for memory decline in aging adults with autism.

How similar studies have performed: Previous research has shown promising results in using advanced imaging techniques to study neurodegeneration, indicating that this approach may yield valuable insights.

Where this research is happening

Tempe, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.