Investigating melanoma development and potential treatments
Official title: BLRD Research Career Scientist Award Application
Funded at Wm S. Middleton Memorial Veterans Hosp · NIH-11218686 · Data updated 2026-11-12
This study is looking at how melanoma grows and changes, with the goal of finding ways to better predict outcomes and develop new treatments for people with early-stage melanoma, including Veterans and others.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wm S. Middleton Memorial Veterans Hosp NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| NIH project number | 5IK6BX006317-03 |
| Project ID | NIH-11218686 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include Veterans and active service members at increased risk for melanoma, as well as individuals diagnosed with early-stage melanoma.
✕Less likely to help
Patients with advanced melanoma or those not at risk for melanoma may not benefit from this research.
What this research studies
This research focuses on understanding how melanoma tumors develop and progress, particularly looking at the molecular mechanisms involved and the role of the skin environment. The team is working on identifying biomarkers that can help predict outcomes for patients with early-stage melanoma. They are also exploring new treatment strategies by inhibiting specific proteins involved in melanoma growth and using advanced models that mimic human skin to study these processes more accurately. This research aims to improve prevention and treatment options for both Veterans and the general population.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies and treatments for melanoma, potentially improving survival rates and quality of life for patients.
How similar studies have gone: Other research has shown promise in understanding melanoma through similar approaches, but this specific combination of methodologies is relatively novel.
Where this research is happening
-
Wm S. Middleton Memorial Veterans Hosp
Madison, United States Active
Researchers
- Principal investigator: Setaluri, Vijayasaradhi — Wm S. Middleton Memorial Veterans Hosp
- Study coordinator: Setaluri, Vijayasaradhi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.