Investigating medications for alcohol use disorder in people with HIV
Safety and Effectiveness of Medications for Alcohol Use Disorder among HIV+/-
This study is looking at how certain medications for alcohol use disorder can help people living with HIV, especially since they often have other health issues, and it aims to find safe and effective ways to reduce alcohol use and liver damage in these individuals.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10906199 on NIH RePORTER |
What this research studies
This research focuses on understanding how medications for alcohol use disorder (AUD) can be safely and effectively used among individuals living with HIV. It addresses the challenges faced by healthcare providers who are often unfamiliar with these medications and the complexities of treating patients with multiple health issues. By analyzing large-scale real-world data, the study aims to identify existing medications that could be repurposed to help reduce alcohol consumption and liver damage in this population. The research will also explore the effectiveness of FDA-approved AUD medications in the context of polypharmacy and physiological frailty.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who also have alcohol use disorder.
Not a fit: Patients who do not have HIV or alcohol use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for individuals with HIV who struggle with alcohol use disorder, potentially reducing morbidity and mortality.
How similar studies have performed: Previous research has shown promise in repurposing medications for various conditions, indicating potential success for this approach in the context of AUD and HIV.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Edelman, E. Jennifer — Yale University
- Study coordinator: Edelman, E. Jennifer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.