Investigating medication use among people living with dementia

Prescribing without a guide: A national study of psychotropic and opioid polypharmacy among persons living with dementia

NIH-funded research University of Michigan at Ann Arbor · NIH-11001483

This study looks at how often people with dementia are given multiple medications, especially those for mental health and pain, to find safer ways to manage their treatment and improve their health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11001483 on NIH RePORTER

What this research studies

This research examines how medications, particularly psychotropic and opioid drugs, are prescribed to individuals living with dementia. It focuses on the prevalence of polypharmacy, which is the use of multiple medications that may pose risks to older adults. By analyzing prescription patterns and their effects on health outcomes, the study aims to identify safer medication practices for this vulnerable population. The research will involve data collection from various healthcare settings to understand the complexities of medication management in dementia care.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias who are currently prescribed multiple medications.

Not a fit: Patients who are not living with dementia or those who are not on multiple psychotropic or opioid medications may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved medication safety and better health outcomes for patients living with dementia.

How similar studies have performed: Previous research has highlighted the risks associated with polypharmacy in older adults, indicating that this area of study is critical and has the potential for significant advancements in patient care.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorder
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.