Investigating lung inflammation and fibrosis using molecular imaging
Molecular Imaging CCR2 Lung Inflammation and Fibrosis
This study is looking at a new way to use PET scans to find specific immune cells in the lungs of people with idiopathic pulmonary fibrosis (IPF), with the goal of developing better treatments to help improve their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11003317 on NIH RePORTER |
What this research studies
This research focuses on understanding pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF), which is challenging to diagnose and treat. The study aims to develop a molecular imaging technique using positron-emission tomography (PET) to detect specific inflammatory cells in the lungs that are linked to fibrosis. By identifying these cells, the researchers hope to create targeted therapies that can improve patient outcomes. The approach builds on previous findings that certain immune cells play a significant role in the progression of lung fibrosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with idiopathic pulmonary fibrosis or other forms of lung fibrosis.
Not a fit: Patients with lung conditions unrelated to fibrosis or those who do not have a diagnosis of pulmonary fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and targeted treatments for patients suffering from pulmonary fibrosis.
How similar studies have performed: Previous research has shown promise in using molecular imaging techniques for similar conditions, indicating potential for success in this approach.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Brody, Steven — Washington University
- Study coordinator: Brody, Steven
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.