Investigating lung function abnormalities in people living with HIV
Isolated Abnormality in the Diffusion Capacity for Carbon Monoxide in People Living with HIV – Epidemiology, Etiology and Pathogenesis
This study is looking at a lung issue called isolated decreased diffusion capacity for carbon monoxide (iso↓DLco) that affects people living with HIV, to better understand how it relates to inflammation and other health factors, and to help improve lung health for those individuals.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10899595 on NIH RePORTER |
What this research studies
This research focuses on understanding a specific lung function abnormality known as isolated decreased diffusion capacity for carbon monoxide (iso↓DLco) in individuals living with HIV. It aims to explore the clinical significance of this condition, which is more prevalent in people with HIV compared to the general population. The study will analyze the relationship between iso↓DLco and various inflammatory and immune biomarkers, as well as potential underlying causes such as chronic lung disease or co-infections. By examining these factors, the research seeks to uncover the pathophysiology of iso↓DLco and its implications for respiratory health in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who exhibit respiratory symptoms or have abnormal lung function tests.
Not a fit: Patients who do not have HIV or those without respiratory symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of respiratory symptoms in people living with HIV.
How similar studies have performed: Previous research has indicated that similar approaches to studying lung function in HIV-positive populations have yielded valuable insights, suggesting potential for success in this investigation.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Byanova, Katerina L. — University of California, San Francisco
- Study coordinator: Byanova, Katerina L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.