Investigating lung disease related to systemic sclerosis and blood vessel damage
Vasculopathy and Systemic Sclerosis-Associated Interstitial Lung Disease
This study is looking at how problems with blood vessels might affect lung health in people with systemic sclerosis, and it aims to help find better treatments for lung disease by examining 100 adults with this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10888282 on NIH RePORTER |
What this research studies
This research focuses on understanding how damage to blood vessels and the microvascular system contributes to lung disease in patients with systemic sclerosis (SSc). By studying a group of 100 adults with SSc, the researchers aim to explore the connections between lung function, blood vessel health, and the development of interstitial lung disease (ILD). The study will use various methods, including imaging and blood tests, to gather data on how these factors interact and potentially lead to new treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with systemic sclerosis, particularly those showing early signs of lung involvement.
Not a fit: Patients without a diagnosis of systemic sclerosis or those with other unrelated lung conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new ways to prevent or treat lung disease in patients with systemic sclerosis.
How similar studies have performed: While there has been significant research on systemic sclerosis and lung disease, this specific approach targeting microvascular injury as a treatment avenue is relatively novel.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Bernstein, Elana — Columbia University Health Sciences
- Study coordinator: Bernstein, Elana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.