Investigating lung disease in systemic sclerosis to find new treatments
From proteomics and genomics to therapeutics in systemic sclerosis interstitial lung disease
This study is looking at how lung problems happen in people with systemic sclerosis, hoping to find new ways to help improve lung health by examining proteins and genes related to the disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10929343 on NIH RePORTER |
What this research studies
This research focuses on understanding how lung disease develops in patients with systemic sclerosis, a condition that can lead to serious complications like interstitial lung disease. By analyzing proteins and genetic factors involved in this disease, the researchers aim to identify new targets for drug development. They will use advanced technologies to characterize the lung's protein composition, which could reveal potential new therapies to improve lung function and overall health for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with systemic sclerosis who are experiencing lung complications.
Not a fit: Patients without systemic sclerosis or those whose lung function is not affected by the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that stop or reverse lung damage in patients with systemic sclerosis.
How similar studies have performed: Previous research has shown promise in targeting similar pathways in other fibrotic diseases, indicating potential for success in this novel approach.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Eickelberg, Oliver — University of Pittsburgh at Pittsburgh
- Study coordinator: Eickelberg, Oliver
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.