Investigating lung cancer screening in patients with other health conditions

Comorbidity and Functional Status in a Population Undergoing Lung Cancer Screening

NIH-funded research Univ of North Carolina Chapel Hill · NIH-10650152

This study is looking at how lung cancer screening with low-dose CT scans can help people who have other health problems or limitations, so we can better understand the benefits and risks for those who might not be as healthy as usual.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-10650152 on NIH RePORTER

What this research studies

This research focuses on understanding how lung cancer screening impacts patients who have other health issues or functional limitations. It aims to evaluate the effectiveness of low-dose computed tomography (LDCT) for lung cancer detection in individuals who may not be as healthy as those typically included in previous studies. By examining a broader population, the research seeks to provide insights into the risks and benefits of lung cancer screening for these patients. The study will analyze data from participants to determine how comorbidities affect screening outcomes and treatment eligibility.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 55 to 80 years who are current or former smokers with a significant smoking history and have other health conditions.

Not a fit: Patients who are healthy and do not have a history of smoking or comorbid conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved lung cancer screening protocols that better accommodate patients with multiple health conditions.

How similar studies have performed: While there has been significant research on lung cancer screening, this specific focus on patients with comorbidities is relatively novel and has not been extensively tested.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast CancerDiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.