Investigating long-term health outcomes in older adults with type 2 diabetes and obesity
Action for Health in Diabetes (Look AHEAD) Extended Follow-up (LA-E2)
This study is looking at how weight loss programs can help older adults with type 2 diabetes and obesity live healthier and happier lives as they age, by tracking their health over many years to find the best ways to support their independence and well-being.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project ID | NIH-10900450 on NIH RePORTER |
What this research studies
This research focuses on understanding how behavioral interventions aimed at weight loss can improve health outcomes for older adults with type 2 diabetes and obesity. By following a cohort of individuals who have been studied for 18 years, the project aims to identify factors that contribute to healthier aging and resilience. Participants will be monitored for major health events, healthcare utilization, and other relevant outcomes to assess the long-term effects of lifestyle changes. The goal is to find effective strategies that can help maintain independence and quality of life as individuals age.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 21 and above who have been diagnosed with type 2 diabetes and are experiencing overweight or obesity.
Not a fit: Patients who do not have type 2 diabetes or who are not overweight or obese may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved health and quality of life for older adults living with type 2 diabetes and obesity.
How similar studies have performed: Previous research has shown that behavioral interventions can be effective in managing weight and improving health outcomes in similar populations, indicating a promising approach.
Where this research is happening
Winston-Salem, United States
- Wake Forest University Health Sciences — Winston-Salem, United States (Active)
Researchers
- Principal investigator: Espeland, Mark Andrew — Wake Forest University Health Sciences
- Study coordinator: Espeland, Mark Andrew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.