Investigating long-term cognitive effects of COVID-19 in older African Americans

Post COVID-19 Neuro-Cognitive Manifestations and Underlying Mechanisms in Older African Americans

NIH-funded research Ut Southwestern Medical Center · NIH-10423708

This study is looking at how COVID-19 might affect thinking and memory in older African Americans who had symptoms of the virus, and it’s for people aged 50 and up who want to help us understand these long-lasting effects.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center NIH-funded
Lab location1 site (Dallas, United States)
Project IDNIH-10423708 on NIH RePORTER

What this research studies

This research focuses on understanding the long-term neuro-cognitive effects of COVID-19 in older African Americans, particularly those who have experienced symptoms of the virus. It aims to identify the prevalence and characteristics of cognitive impairments that persist beyond the acute phase of infection. Participants, aged 50 and older, will undergo a series of assessments including cognitive tests, neuroimaging, and cardiovascular evaluations to explore the underlying mechanisms of these impairments. The study seeks to provide insights into how COVID-19 affects daily living and quality of life in this vulnerable population.

Who could benefit from this research

Good fit: Ideal candidates for this research are African Americans aged 50 and older who have a history of COVID-19 infection, whether symptomatic or asymptomatic.

Not a fit: Patients who are younger than 50 or who have not had a COVID-19 infection may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of cognitive impairments in older African Americans post-COVID-19.

How similar studies have performed: Other research has indicated that similar approaches to studying long-term effects of viral infections on cognitive function have shown promising results, suggesting potential for success in this area.

Where this research is happening

Dallas, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.