Investigating liver diseases related to bile acids and sphingolipids
BLR&D Research Career Scientist Award Application
This study is looking at how certain substances in the body, like bile acids and sphingolipids, impact liver health and diseases, especially for people with alcoholic liver disease and non-alcoholic fatty liver disease, to help find better ways to diagnose and treat these conditions for everyone, including Veterans.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Veterans Administration Hospital NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-10951538 on NIH RePORTER |
What this research studies
This research focuses on understanding how bile acids and sphingolipids affect liver function and disease progression in conditions such as alcoholic liver disease and non-alcoholic fatty liver disease. By using advanced animal models, the research aims to uncover the complex signaling pathways involved in liver health and disease. The findings could lead to new diagnostic markers and treatments for chronic liver diseases, benefiting both Veterans and the general population.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from chronic liver diseases, particularly those related to alcohol consumption or metabolic disorders.
Not a fit: Patients with acute liver conditions or those without liver disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments and better management strategies for chronic liver diseases.
How similar studies have performed: Previous research has shown promise in understanding liver diseases through similar signaling pathway investigations, indicating a potential for success in this area.
Where this research is happening
Richmond, United States
- VA Veterans Administration Hospital — Richmond, United States (Active)
Researchers
- Principal investigator: Zhou, Huiping Rose — VA Veterans Administration Hospital
- Study coordinator: Zhou, Huiping Rose
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.