Investigating liver cancer linked to HIV and viral infections in Africa
H2A Developmental Core
This study is looking at how certain infections, like hepatitis B and C, HIV, and Schistosomiasis, can lead to liver cancer in people in Africa, especially those living with HIV, and it aims to find ways to prevent this cancer while helping local researchers grow their skills.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10903771 on NIH RePORTER |
What this research studies
This research focuses on hepatocellular carcinoma (HCC), a common and deadly cancer in Africa, particularly among patients living with HIV. The project aims to understand how chronic infections with hepatitis B and C viruses, along with HIV and Schistosomiasis, contribute to the development of HCC. By fostering partnerships between institutions in East and West Africa, the research seeks to develop local capacity and implement cancer interception strategies to reduce the burden of HCC. The initiative also supports early-stage African investigators through mentorship and pilot projects.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living with HIV and chronic hepatitis B or C infections in sub-Saharan Africa.
Not a fit: Patients without HIV or chronic viral infections, or those outside the sub-Saharan African region, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for liver cancer in patients with HIV and viral infections.
How similar studies have performed: Previous research has shown success in addressing similar health challenges in Africa, indicating potential for impactful outcomes in this area.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Kirk, Gregory D — Johns Hopkins University
- Study coordinator: Kirk, Gregory D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.