Investigating liver cancer linked to HIV and viral infections in Africa
H2A Clinical Core
This study is looking at how certain infections, like hepatitis and HIV, can lead to liver cancer in people in Africa, especially those living with HIV, and aims to find ways to prevent or treat this cancer more effectively.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10903768 on NIH RePORTER |
What this research studies
This research focuses on hepatocellular carcinoma (HCC), a common and deadly cancer in Africa, particularly among patients living with HIV. The project aims to understand the relationship between chronic infections like hepatitis B and C, HIV, and schistosomiasis, which are known risk factors for HCC. By collaborating with institutions across East and West Africa, the research seeks to develop strategies to interrupt or reverse the impact of these infections on liver cancer. The study will involve rigorous data collection and analysis to inform better treatment and prevention strategies for HCC in affected populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living with HIV who are at risk for hepatocellular carcinoma due to chronic viral infections.
Not a fit: Patients who do not have HIV or chronic viral infections related to liver cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for liver cancer in HIV-positive patients in Africa.
How similar studies have performed: Previous research has shown success in addressing similar health challenges in Africa, indicating that this approach has the potential for meaningful impact.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Aizire, Jim — Johns Hopkins University
- Study coordinator: Aizire, Jim
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.