Investigating liver cancer linked to HIV and viral infections in Africa
H2A Admin Core
This study is looking at how certain infections, like hepatitis and HIV, can increase the risk of liver cancer in people in Africa, especially those living with HIV, and it aims to find better ways to prevent and treat this cancer through teamwork between universities in East and West Africa.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10903766 on NIH RePORTER |
What this research studies
This research focuses on hepatocellular carcinoma (HCC), a common and deadly cancer in Africa, particularly among patients living with HIV. It aims to understand the relationship between chronic infections like hepatitis B and C, HIV, and Schistosomiasis mansoni as risk factors for HCC. The study involves collaboration between institutions in East and West Africa, including Makerere University and Fann University, to develop strategies for cancer interception and improve patient outcomes. The project emphasizes the importance of effective organizational leadership and international collaboration to tackle this pressing health issue.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV in sub-Saharan Africa who are at risk for developing hepatocellular carcinoma.
Not a fit: Patients who do not have HIV or chronic viral infections related to liver cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for liver cancer in HIV-infected patients in Africa.
How similar studies have performed: Previous research has shown success in addressing similar health challenges through international collaborations focused on infectious diseases and cancer.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Kirk, Gregory D — Johns Hopkins University
- Study coordinator: Kirk, Gregory D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.