Investigating lipidated amino acids in heart and liver diseases
Official title: Lipidated Amino Acids in Cardiometabolic Diseases
Funded at Louisiana State Univ Hsc Shreveport · NIH-11058494 · Data updated 2026-11-12
This study is looking at how certain fatty-linked amino acids affect liver health and heart disease, with the goal of finding new ways to help people with non-alcoholic fatty liver disease and related heart issues, and it may involve patients sharing samples or information to help with the research.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ Hsc Shreveport NIH-funded |
| Lab location | 1 site (Shreveport, United States) |
| Project start | June 2, 2022 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $429,581 |
| NIH project number | 5R01DK134011-04 |
| Project ID | NIH-11058494 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with non-alcoholic fatty liver disease or those at risk for atherosclerosis.
✕Less likely to help
Patients without any liver disease or cardiovascular risk factors may not benefit from this research.
What this research studies
This research focuses on understanding how lipidated amino acids, which are linked to fatty acids, play a role in non-alcoholic fatty liver disease (NAFLD) and atherosclerosis. The study aims to explore the metabolic pathways of these amino acids and their potential impact on cardiometabolic diseases. By examining liver metabolism and the regulation of these compounds, the research seeks to identify new therapeutic targets for treating conditions like NAFLD and its associated cardiovascular risks. Patients may be involved in providing samples or data to help uncover these metabolic mechanisms.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for patients suffering from NAFLD and related cardiovascular diseases.
How similar studies have gone: While the specific approach of targeting lipidated amino acids is relatively novel, there is growing interest in metabolic pathways related to NAFLD and cardiovascular diseases, suggesting potential for success.
Where this research is happening
-
Louisiana State Univ Hsc Shreveport
Shreveport, United States Active
Researchers
- Principal investigator: Rom, Oren Shalom — Louisiana State Univ Hsc Shreveport
- Study coordinator: Rom, Oren Shalom
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.