Investigating lipid mediators in eye inflammation and meibomian gland dysfunction
Official title: Lipid mediators and their signaling in ocular surface inflammation and meibomian gland dysfunction
Funded at Miami VA Health Care System · NIH-11219727 · Data updated 2026-11-12
This study is looking at how certain fats in your tears might be causing dry eye symptoms, especially for veterans, and aims to find out how these fats affect eye inflammation and tear production.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Miami VA Health Care System NIH-funded |
| Lab location | 1 site (Miami, United States) |
| Project start | October 1, 2020 |
| Project end | September 30, 2025 |
| Funding year | 2025 |
| NIH project number | 5I01BX004893-05 |
| Project ID | NIH-11219727 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans experiencing symptoms of dry eye disease, such as pain and visual disturbances.
✕Less likely to help
Patients who do not have dry eye disease or related ocular surface conditions may not benefit from this research.
What this research studies
This research focuses on understanding dry eye disease, which affects many veterans and can significantly impact their quality of life. It aims to explore the role of specific lipids in the inflammation of the ocular surface and dysfunction of the meibomian glands, which are crucial for tear production. By analyzing changes in lipid composition in tears and meibomian gland secretions, the study seeks to identify the underlying mechanisms contributing to dry eye symptoms. The research will involve laboratory assays and analyses to determine how these lipids influence inflammation and tear film stability.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for dry eye disease, enhancing the quality of life for affected patients.
How similar studies have gone: Previous research has shown promising results in understanding the role of lipid mediators in inflammation, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Miami VA Health Care System
Miami, United States Active
Researchers
- Principal investigator: Galor, Anat — Miami VA Health Care System
- Study coordinator: Galor, Anat
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.