Investigating light sensitivity and pupil response in headaches after trauma

Photophobia and Pupillary Autonomic Dysfunction as Biomarkers of Post-Traumatic Headache

NIH-funded research University of Utah · NIH-10814234

This study is looking at how sensitivity to light and how your pupils react can help us understand headaches that happen after a concussion, and it’s for people who experience these headaches to help improve their diagnosis and treatment.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-10814234 on NIH RePORTER

What this research studies

This research focuses on understanding how light sensitivity (photophobia) and pupil response are related to post-traumatic headaches, which often occur after a concussion. The principal investigator, Dr. Melissa Cortez, aims to develop objective measures for diagnosing and tracking the progression of this debilitating condition. By utilizing advanced techniques in biostatistics and visual function testing, the research seeks to identify biomarkers that can help in the management and treatment of post-traumatic headaches. Patients may be involved in assessments that evaluate their sensory responses to light and other stimuli.

Who could benefit from this research

Good fit: Ideal candidates for participation are individuals who have experienced a concussion and are suffering from post-traumatic headaches.

Not a fit: Patients who do not have a history of concussion or do not experience headaches may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment options for patients suffering from post-traumatic headaches.

How similar studies have performed: Other research has shown promise in identifying biomarkers for headache disorders, suggesting that this approach may yield valuable insights.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.