Investigating kidney tubule health and its role in chronic kidney disease

Kidney Tubular Damage and Dysfunction Identify a Novel Axis of Chronic Kidney Disease

NIH-funded research Veterans Medical Research Fdn/san Diego · NIH-10683087

This study is looking at how healthy kidney tubules are and how they can help us understand and predict the progression of chronic kidney disease, especially in relation to managing blood pressure, so we can find better ways to care for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVeterans Medical Research Fdn/san Diego NIH-funded
Lab location1 site (San Diego, United States)
Project IDNIH-10683087 on NIH RePORTER

What this research studies

This research focuses on understanding the health of kidney tubules, which play a crucial role in various kidney functions. Unlike traditional methods that primarily assess glomerular filtration rate and damage, this project aims to identify non-invasive biomarkers that can provide insights into tubule health and predict chronic kidney disease progression. By analyzing data from a significant clinical trial, the researchers hope to uncover new relationships between blood pressure management and kidney tubule injury, potentially leading to improved patient care strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at risk for chronic kidney disease or those with existing kidney dysfunction.

Not a fit: Patients with acute kidney injury or those not at risk for chronic kidney disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better methods for monitoring kidney health and preventing chronic kidney disease progression.

How similar studies have performed: Previous research has shown promise in using non-invasive biomarkers to assess kidney health, indicating that this approach may lead to significant advancements in understanding chronic kidney disease.

Where this research is happening

San Diego, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular Diseasescardiovascular disorder
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.