Investigating kidney tubule health and its role in chronic kidney disease
Official title: Kidney Tubular Damage and Dysfunction Identify a Novel Axis of Chronic Kidney Disease
Funded at Veterans Medical Research Fdn/san Diego · NIH-10683087 · Data updated 2026-11-12
This study is looking at how healthy kidney tubules are and how they can help us understand and predict the progression of chronic kidney disease, especially in relation to managing blood pressure, so we can find better ways to care for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Medical Research Fdn/san Diego NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | September 20, 2019 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $591,938 |
| NIH project number | 5R01DK098234-09 |
| Project ID | NIH-10683087 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for chronic kidney disease or those with existing kidney dysfunction.
✕Less likely to help
Patients with acute kidney injury or those not at risk for chronic kidney disease may not benefit from this research.
What this research studies
This research focuses on understanding the health of kidney tubules, which play a crucial role in various kidney functions. Unlike traditional methods that primarily assess glomerular filtration rate and damage, this project aims to identify non-invasive biomarkers that can provide insights into tubule health and predict chronic kidney disease progression. By analyzing data from a significant clinical trial, the researchers hope to uncover new relationships between blood pressure management and kidney tubule injury, potentially leading to improved patient care strategies.
Why it matters
Potential benefit: If successful, this research could lead to better methods for monitoring kidney health and preventing chronic kidney disease progression.
How similar studies have gone: Previous research has shown promise in using non-invasive biomarkers to assess kidney health, indicating that this approach may lead to significant advancements in understanding chronic kidney disease.
Where this research is happening
-
Veterans Medical Research Fdn/san Diego
San Diego, United States Active
Researchers
- Principal investigator: Ix, Joachim H — Veterans Medical Research Fdn/san Diego
- Study coordinator: Ix, Joachim H
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.