Investigating kidney tubule health and its impact on heart disease in older adults
Dimensions of Kidney Tubule Health and Atherosclerotic Cardiovascular Disease and Heart Failure in Middle-Aged and Older Adults
This study is looking at how the health of tiny tubes in your kidneys might influence your chances of developing heart disease as you get older, using new urine tests to find out more about your kidney health and help identify those who may be at higher risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tufts Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10990998 on NIH RePORTER |
What this research studies
This research focuses on understanding how the health of kidney tubules affects the risk of heart disease and heart failure in middle-aged and older adults. It utilizes novel urine tests to measure various aspects of kidney tubule health, which are believed to be more indicative of cardiovascular risks than traditional kidney function tests. By analyzing these urine measures, the research aims to identify high-risk individuals and improve patient outcomes through better risk assessment and management strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are middle-aged and older adults with chronic kidney disease who are at risk for cardiovascular disease.
Not a fit: Patients without chronic kidney disease or those who are younger than middle age may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for predicting and preventing heart disease and heart failure in patients with chronic kidney disease.
How similar studies have performed: Previous research has shown that assessing kidney tubule health can provide valuable insights into cardiovascular risks, suggesting that this approach may yield significant findings.
Where this research is happening
Boston, United States
- Tufts Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Sarnak, Mark J — Tufts Medical Center
- Study coordinator: Sarnak, Mark J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.