Investigating kidney tubule function to predict acute kidney injury risk
Kidney Tubule Dysfunction and Future Risk of Acute Kidney Injury
This study is looking at how certain kidney problems can help doctors spot people who might be at risk for sudden kidney injury, even if they seem healthy, so they can take steps to prevent it, especially in cases like infections or heart issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10813027 on NIH RePORTER |
What this research studies
This research focuses on understanding how abnormalities in kidney tubule function can predict the risk of acute kidney injury (AKI) in patients. By analyzing blood and urine samples from a large cohort of participants, the study aims to identify individuals who may be at risk for AKI before it occurs, even if they appear healthy. The researchers will explore how these kidney function abnormalities relate to common clinical scenarios such as sepsis and heart failure. If successful, this research could lead to new strategies for preventing AKI through tailored medical interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of conditions like heart failure or those undergoing procedures such as coronary artery bypass graft surgery.
Not a fit: Patients with established chronic kidney disease or those who have already experienced acute kidney injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could help identify patients at risk for acute kidney injury, allowing for preventive measures that could save lives and reduce healthcare costs.
How similar studies have performed: Previous studies have shown promise in identifying kidney function abnormalities as predictors of acute kidney injury, suggesting that this approach may be effective.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Ix, Joachim H — University of California, San Diego
- Study coordinator: Ix, Joachim H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.