Investigating kidney injury using small animal models
Official title: Pre-Clinical Core
Funded at University of Alabama at Birmingham · NIH-10915662 · Data updated 2026-11-12
This study is looking at how kidney injuries happen in mice to help us learn more about conditions like sepsis and other issues that can harm our kidneys, with the goal of finding better treatments for people with acute kidney injury.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $252,298 |
| NIH project number | 5U54DK137307-02 |
| Project ID | NIH-10915662 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for acute kidney injury, such as those undergoing major surgeries or with conditions like sepsis.
✕Less likely to help
Patients with chronic kidney disease or those who do not have acute kidney injury may not benefit from this research.
What this research studies
This research focuses on understanding acute kidney injury (AKI) through the use of small animal models, specifically mice. It aims to provide facilities and expertise to study the physiological changes in kidneys affected by conditions like ischemia/reperfusion injury and sepsis. The research will utilize advanced techniques to analyze kidney function at both the whole organ and cellular levels, helping to develop new therapeutic approaches for AKI. By sharing specialized knowledge and resources, this project seeks to enhance the understanding of kidney health and disease.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and preventive strategies for acute kidney injury.
How similar studies have gone: Previous research using small animal models has shown promise in understanding kidney diseases and developing new treatments.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Sanders, Paul W. — University of Alabama at Birmingham
- Study coordinator: Sanders, Paul W.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.