Investigating kidney injury caused by COVID-19 using nonhuman primate models.
COVID-19 and Kidney Injury: Urinary Transcriptomics of Kidney Injury in Novel Nonhuman Primate Models of SARS-CoV-2
['FUNDING_R21'] · TULANE UNIVERSITY OF LOUISIANA · NIH-10689671
This study is looking at how COVID-19 can harm kidney function, especially in people who experience acute kidney injury, using nonhuman primates to help us understand the problem better and find new ways to help those affected.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TULANE UNIVERSITY OF LOUISIANA (nih funded) |
| Locations | 1 site (NEW ORLEANS, UNITED STATES) |
| Trial ID | NIH-10689671 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how COVID-19 affects kidney function, particularly through the lens of acute kidney injury (AKI). By utilizing nonhuman primate models, which closely resemble human anatomy and immune responses, the study aims to explore the mechanisms behind kidney damage associated with SARS-CoV-2 infection. Researchers will analyze urinary transcriptomics to identify biomarkers and pathways involved in kidney injury, potentially leading to better treatment strategies for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with COVID-19 who are experiencing or at risk of acute kidney injury.
Not a fit: Patients who do not have COVID-19 or those without any kidney-related complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of kidney injury in COVID-19 patients, ultimately enhancing patient outcomes.
How similar studies have performed: Previous research using nonhuman primate models for respiratory viral infections has shown promise, indicating that this approach could yield valuable insights.
Where this research is happening
NEW ORLEANS, UNITED STATES
- TULANE UNIVERSITY OF LOUISIANA — NEW ORLEANS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PRIETO, MINOLFA C — TULANE UNIVERSITY OF LOUISIANA
- Study coordinator: PRIETO, MINOLFA C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.