Investigating key factors that drive aggressive brain tumors.
Official title: Collaborative Activities of the Key Transcription Factors in Glioblastoma Stem-like Cancer Cells
Funded at Texas A&m University-Kingsville · NIH-10804746 · Data updated 2026-11-12
This study is looking at a type of brain tumor called glioblastoma to find out how certain proteins help cancer cells grow and survive, with the hope of discovering new ways to get rid of these tough cells and improve treatment for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas A&m University-Kingsville NIH-funded |
| Lab location | 1 site (Kingsville, United States) |
| Project start | May 1, 2021 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $103,500 |
| NIH project number | 5SC3GM141756-04 |
| Project ID | NIH-10804746 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults diagnosed with glioblastoma multiforme, particularly those with aggressive forms of the disease.
✕Less likely to help
Patients with other types of brain tumors or those who are not diagnosed with glioblastoma may not benefit from this research.
What this research studies
This research focuses on glioblastoma multiforme (GBM), a highly aggressive brain tumor with a poor prognosis. It aims to understand the role of specific transcription factors in the development and maintenance of stem-like cancer cells within GBM. By identifying genes controlled by these factors, the research seeks to develop innovative techniques to eliminate these harmful cells, potentially improving treatment outcomes for patients. The study employs advanced molecular biology techniques to explore the interactions between transcription factors and their target genes.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve survival rates for patients with glioblastoma.
How similar studies have gone: While the approach of targeting transcription factors in glioblastoma is innovative, similar strategies have shown promise in other cancer types, indicating potential for success.
Where this research is happening
-
Texas A&m University-Kingsville
Kingsville, United States Active
Researchers
- Principal investigator: Sung, Chang Kyoo — Texas A&m University-Kingsville
- Study coordinator: Sung, Chang Kyoo
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CD38-Driven Changes in Brain Tumor Metabolism and Immunity in Glioblastoma
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.