Investigating Kaiso as a breast cancer biomarker in women of African ancestry
The Role of Kaiso as a predictive breast cancer biomarker in Africa and across the African Diaspora
This study is looking at a special marker called Kaiso in breast cancer to see how it can help us understand how aggressive the cancer might be and how well patients might do, especially for women of African ancestry and those in the African Diaspora, with the hope of finding better treatment options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10910070 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of the Kaiso biomarker in breast cancer among women of African ancestry and the African Diaspora. It aims to explore how the presence and location of Kaiso within breast cancer cells can predict tumor aggressiveness and patient outcomes. By analyzing tumor samples and their biological behavior, the study seeks to identify specific patterns that could lead to better treatment strategies. The research also examines the relationship between Kaiso and the tumor microenvironment, which may influence cancer progression and response to therapy.
Who could benefit from this research
Good fit: Ideal candidates for this research are women of African ancestry who are diagnosed with breast cancer.
Not a fit: Patients who do not have African ancestry or those without a breast cancer diagnosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved predictive tools for breast cancer outcomes in women of African descent, ultimately enhancing personalized treatment approaches.
How similar studies have performed: Previous research has indicated the potential of biomarkers like Kaiso in predicting breast cancer outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Gardner, Kevin L. — Columbia University Health Sciences
- Study coordinator: Gardner, Kevin L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.