Investigating intestinal fibrosis and inflammation in Crohn's Disease using advanced imaging techniques
Assessing biomarkers of intestinal fibrosis and inflammation in Crohn's Disease via an endoscopic imaging catheter
This study is looking at a new way to help doctors better understand Crohn's Disease by using a special tool to see signs of inflammation and scarring in the intestines, which can help tell if a patient needs medication or surgery, ultimately aiming to improve treatment and health for those living with the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10908285 on NIH RePORTER |
What this research studies
This research focuses on improving the diagnosis of Crohn's Disease by using an endoscopic imaging catheter to assess biomarkers of intestinal fibrosis and inflammation. The study aims to differentiate between acute inflammatory strictures, which can be treated with medication, and chronic strictures that may require surgery. By combining molecular markers and mechanical assessments, the research seeks to provide a more accurate characterization of intestinal damage. This could lead to better treatment decisions and improved patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Crohn's Disease who are experiencing intestinal strictures.
Not a fit: Patients with Crohn's Disease who do not have strictures or those with other gastrointestinal conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and tailored treatments for patients with Crohn's Disease.
How similar studies have performed: Previous studies have shown promise in using advanced imaging techniques for diagnosing intestinal conditions, suggesting that this approach could be effective.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Higgins, Peter D.r. — University of Michigan at Ann Arbor
- Study coordinator: Higgins, Peter D.r.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.