Investigating inflammation networks in Alzheimer's and frontotemporal disorders
Official title: Multi-omic integrative analysis of shared and distinct inflammation networks across neurodegenerative disorders
Funded at Methodist Hospital Research Institute · NIH-11170832 · Data updated 2026-11-12
This study is looking at how inflammation affects Alzheimer's disease and frontotemporal disorder by comparing blood samples from patients and healthy people, with the hope of finding new ways to treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Methodist Hospital Research Institute NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 30, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $760,207 |
| NIH project number | 1R56AG085576-01 |
| Project ID | NIH-11170832 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or frontotemporal disorder.
✕Less likely to help
Patients with neurodegenerative disorders other than Alzheimer's or frontotemporal disorder may not benefit from this research.
What this research studies
This research focuses on understanding the role of inflammation in Alzheimer's disease (AD) and frontotemporal disorder (FTD), two common neurodegenerative conditions. By analyzing blood samples from patients with these disorders and healthy individuals, the study aims to identify specific inflammatory markers and pathways that are activated in each condition. The goal is to uncover shared and unique inflammatory responses that could lead to new treatment strategies targeting inflammation. Patients may be involved in providing blood samples and contributing to the understanding of their condition.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic approaches that target inflammation, potentially improving outcomes for patients with Alzheimer's and frontotemporal disorders.
How similar studies have gone: Previous research has shown promising results in targeting inflammation as a treatment strategy for neurodegenerative diseases, suggesting that this approach may be viable.
Where this research is happening
-
Methodist Hospital Research Institute
Houston, United States Active
Researchers
- Principal investigator: Faridar, Alireza — Methodist Hospital Research Institute
- Study coordinator: Faridar, Alireza
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.