Investigating immune responses to COVID-19 and influenza in older adults
Official title: Core B - Clinical Core
Funded at Washington University · NIH-10824576 · Data updated 2026-11-12
This study is looking at how the immune system of people aged 65 and older reacts to COVID-19 and flu vaccines, with the goal of finding better ways to protect their health through improved vaccination and treatment options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 4, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $455,453 |
| NIH project number | 1U19AI181103-01 |
| Project ID | NIH-10824576 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are individuals aged 65 and older who are interested in contributing to research on COVID-19 and influenza.
✕Less likely to help
Patients who are younger than 65 years old or those not affected by COVID-19 or influenza may not benefit from this research.
What this research studies
This research focuses on understanding how the immune system responds to infections and vaccinations for COVID-19 and influenza, particularly in individuals aged 65 and older. The study combines resources from experienced clinical research units at Washington University, utilizing advanced methodologies to collect and analyze clinical samples and data. Patients may participate in clinical trials that aim to improve vaccination strategies and treatment options for older adults, enhancing their overall health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccination strategies and treatments for older adults, enhancing their immune responses to infections.
How similar studies have gone: Previous research has shown success in understanding immune responses to vaccines in older populations, indicating a promising avenue for this study.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Presti, Rachel Margaret — Washington University
- Study coordinator: Presti, Rachel Margaret
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.