Investigating immune responses related to neurological issues from COVID-19

Humoral Immune Mechanisms of Acute and Chronic Neurologic Sequelae of COVID-19

NIH-funded research University of California, San Francisco · NIH-10992116

This study is looking at how COVID-19 might cause brain and nerve problems, like encephalitis and Guillain-Barré syndrome, and aims to find specific markers in patients that could help doctors better understand and treat these issues.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10992116 on NIH RePORTER

What this research studies

This research focuses on understanding the immune mechanisms behind neurological complications that arise from COVID-19, such as encephalitis and Guillain-Barré syndrome. The team at UCSF aims to identify specific biomarkers that indicate autoimmune responses triggered by the virus, which could help in managing these conditions more effectively. By analyzing patient samples, they will explore the relationship between the virus and neurological symptoms, providing insights into potential treatments. The study involves a cohort of patients with suspected neuroinflammatory diseases, allowing for a comprehensive approach to understanding these complex conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals of all ages who have experienced neurological symptoms following a COVID-19 infection.

Not a fit: Patients who have not had COVID-19 or do not exhibit neurological symptoms related to the virus may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for patients experiencing neurological complications from COVID-19.

How similar studies have performed: Other research has shown promise in identifying autoimmune responses related to viral infections, suggesting that this approach could yield valuable insights.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.