Investigating immune profiles in inflammatory muscle diseases

Immunophenotypes in the Idiopathic Inflammatory Myopathies

NIH-funded research Vanderbilt University Medical Center · NIH-10877796

This study is looking at how the immune system affects muscle inflammation in people with idiopathic inflammatory myopathies (IIM) to find new ways to help improve treatment and care for patients like you.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-10877796 on NIH RePORTER

What this research studies

This research focuses on understanding the immune system's role in idiopathic inflammatory myopathies (IIM), a group of diseases that cause muscle inflammation. The project aims to identify specific immune signatures and transcriptional changes associated with these conditions by analyzing patient samples. By correlating these immune features with clinical outcomes, the research seeks to uncover potential new therapeutic targets and improve patient care. Patients with IIM may have their disease progression better understood through this innovative approach.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with idiopathic inflammatory myopathies.

Not a fit: Patients with other types of muscle diseases or those without a diagnosis of inflammatory myopathy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more personalized treatment options for patients with inflammatory myopathies.

How similar studies have performed: Other research has shown promise in using immune profiling to understand autoimmune diseases, suggesting that this approach could yield valuable insights.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.