Investigating immune factors in preeclampsia risk
Immune activating syncytiotrophoblast microvesicles and danger associated molecular patterns in preeclampsia risk
['FUNDING_R01'] · UNIVERSITY OF TEXAS MED BR GALVESTON · NIH-10655445
This study is looking at tiny particles in the immune system to see if they can help predict the risk of developing preeclampsia during pregnancy, which could lead to better ways to spot and manage this serious condition early on for the health of both moms and babies.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS MED BR GALVESTON (nih funded) |
| Locations | 1 site (GALVESTON, UNITED STATES) |
| Trial ID | NIH-10655445 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the role of immune-activating microvesicles and specific molecular patterns in the risk of developing preeclampsia, a serious pregnancy complication. By analyzing these factors before clinical symptoms appear, the study aims to identify potential biomarkers that could help in early diagnosis and management of preeclampsia. The approach involves large-scale epidemiological investigations to assess the relationship between these immune components and the progression of preeclampsia. This could lead to better monitoring of placental health and improved outcomes for mothers and infants.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women at risk of developing preeclampsia, particularly those with a history of the condition or other related risk factors.
Not a fit: Patients who are not pregnant or those who have already been diagnosed with severe preeclampsia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better management of preeclampsia, reducing risks for both mothers and infants.
How similar studies have performed: While some small studies have shown promising results regarding the role of immune factors in preeclampsia, this research aims to conduct larger investigations that have not been previously explored.
Where this research is happening
GALVESTON, UNITED STATES
- UNIVERSITY OF TEXAS MED BR GALVESTON — GALVESTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHARMA, SURENDRA — UNIVERSITY OF TEXAS MED BR GALVESTON
- Study coordinator: SHARMA, SURENDRA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cardiovascular Diseases, cardiovascular disorder