Investigating immune activation in African Americans with chronic kidney disease.
Biomarkers of Immune Activation in African Americans with CKD
This study is looking at how the immune system affects kidney health in African Americans with chronic kidney disease, aiming to find better ways to treat this condition by tracking certain markers over time.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10702184 on NIH RePORTER |
What this research studies
This research focuses on understanding how immune activation affects the progression of chronic kidney disease (CKD) in African Americans, who are at higher risk due to specific genetic factors. The study will involve measuring biomarkers related to immune response and analyzing their relationship with kidney health over time. Patients will be monitored for changes in their condition, and the research aims to uncover important insights that could lead to better treatment strategies. The project is supported by a team of experienced mentors and will utilize advanced methodologies in epidemiology and data analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American individuals diagnosed with chronic kidney disease, particularly those with APOL1 risk variants.
Not a fit: Patients who do not have chronic kidney disease or those outside the African American demographic may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for African American patients suffering from chronic kidney disease.
How similar studies have performed: Previous research has shown promising results in understanding the role of genetic factors in kidney disease, suggesting that this approach could yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Chen, Teresa — University of California, San Francisco
- Study coordinator: Chen, Teresa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.