Investigating imaging techniques for cervical changes related to preterm birth

Molecular, Functional, and Microstructural Imaging of Cervical Remodeling Biomarkers

['FUNDING_R01'] · UNIVERSITY OF ROCHESTER · NIH-10895849

This study is looking for new ways to take pictures of the cervix to help understand changes that might lead to preterm birth, so that doctors can better predict and manage the risk for expectant moms.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ROCHESTER (nih funded)
Locations1 site (ROCHESTER, UNITED STATES)
Trial IDNIH-10895849 on ClinicalTrials.gov

What this research studies

This research focuses on developing advanced imaging techniques to better understand cervical changes that can lead to preterm birth. By utilizing molecular, functional, and microstructural imaging, the study aims to identify biomarkers associated with cervical insufficiency. The goal is to create non-invasive tools that provide quantitative data on cervical health, which could improve the prediction and management of preterm labor. This approach seeks to enhance current methods that rely heavily on subjective assessments and limited ultrasound capabilities.

Who could benefit from this research

Good fit: Ideal candidates for this research include pregnant women at risk of preterm birth, particularly those with a history of cervical insufficiency or short cervix.

Not a fit: Patients who are not pregnant or those with no history of cervical issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prediction and management of preterm birth, potentially reducing neonatal mortality and healthcare costs.

How similar studies have performed: While there have been advancements in imaging techniques for various medical conditions, this specific approach to cervical imaging in relation to preterm birth is relatively novel and has not been extensively tested.

Where this research is happening

ROCHESTER, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.