Investigating imaging techniques for cervical changes related to preterm birth
Official title: Molecular, Functional, and Microstructural Imaging of Cervical Remodeling Biomarkers
Funded at University of Rochester · NIH-10895849 · Data updated 2026-11-12
This study is looking for new ways to take pictures of the cervix to help understand changes that might lead to preterm birth, so that doctors can better predict and manage the risk for expectant moms.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | July 29, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2023 |
| Award (this year) | $298,561 |
| NIH project number | 7R01EB030058-04 |
| Project ID | NIH-10895849 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant women at risk of preterm birth, particularly those with a history of cervical insufficiency or short cervix.
✕Less likely to help
Patients who are not pregnant or those with no history of cervical issues may not benefit from this research.
What this research studies
This research focuses on developing advanced imaging techniques to better understand cervical changes that can lead to preterm birth. By utilizing molecular, functional, and microstructural imaging, the study aims to identify biomarkers associated with cervical insufficiency. The goal is to create non-invasive tools that provide quantitative data on cervical health, which could improve the prediction and management of preterm labor. This approach seeks to enhance current methods that rely heavily on subjective assessments and limited ultrasound capabilities.
Why it matters
Potential benefit: If successful, this research could lead to improved prediction and management of preterm birth, potentially reducing neonatal mortality and healthcare costs.
How similar studies have gone: While there have been advancements in imaging techniques for various medical conditions, this specific approach to cervical imaging in relation to preterm birth is relatively novel and has not been extensively tested.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Mehrmohammadi, Mohammad — University of Rochester
- Study coordinator: Mehrmohammadi, Mohammad
Related research
Other NIH-funded projects on the same topics.
-
Rapid automated breast lump diagnosis without a radiologist or sonographer
A new AI-powered ultrasound tool helps determine if a palpable breast lump is likely benign or malignant, using a simplified technique that can be used by people with minimal ultrasound training.
-
ML-ROVER: Reducing Unneeded Lab Tests in Kids with AI
Aims to use machine learning to cut unnecessary blood tests in children in intensive care, helping avoid anemia and improve care quality.
-
Aggressive fever-reducing therapy to protect the brains of children with CNS malaria
A study planned for children with CNS malaria will test whether aggressive fever-reducing treatment can lower death and brain-related problems.
-
Aggressive fever-reducing therapy to protect brains in children with CNS malaria
A plan to test whether giving strong fever-reducing medications to children with central nervous system malaria can lower death and brain injury.
-
Aggressive fever-fighting treatment to protect the brain in kids with CNS malaria
A plan to test whether giving strong fever-reducing treatment alongside standard care can lower death and brain injury in children with CNS malaria.
-
Aggressive fever-reducing treatment to protect brains in kids with CNS malaria
A plan to test whether giving strong fever-reducing medicine alongside standard malaria treatment can lower deaths and brain injuries in children with CNS malaria.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.