Investigating imaging responses to immune suppressant therapy in cardiac sarcoidosis patients
Advanced multi-parametric 18F-FDG PET and MRI imaging parameters of response to immune suppressant therapy in patients with active cardiac sarcoidosis
This study is looking at how well certain imaging tests can show if patients with cardiac sarcoidosis are responding to their immune-suppressing treatments, with the goal of finding better ways to help them feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10999907 on NIH RePORTER |
What this research studies
This research focuses on patients with cardiac sarcoidosis, a condition where inflammation affects the heart. It uses advanced imaging techniques, including 18F-FDG PET and MRI, to assess how well patients respond to immune suppressant therapy. By analyzing various imaging parameters, the study aims to establish clear thresholds that indicate treatment effectiveness. This could help optimize therapy strategies and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with active cardiac sarcoidosis who are undergoing or considering immune suppressant therapy.
Not a fit: Patients with cardiac sarcoidosis who are not receiving immune suppressant therapy or those with inactive disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment strategies for patients with cardiac sarcoidosis, potentially improving their heart health and quality of life.
How similar studies have performed: Other research has shown promising results using imaging techniques to assess treatment responses in similar conditions, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Fayad, Zahi a. — Icahn School of Medicine at Mount Sinai
- Study coordinator: Fayad, Zahi a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.