Investigating if statins can help older adults maintain physical function
The PREVENTABLE Physical Performance Ancillary Study
This study is looking at how getting older affects our physical strength and whether taking statins, which are usually for cholesterol, can help older adults stay strong and active, so they can keep doing the things they love.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project ID | NIH-10692800 on NIH RePORTER |
What this research studies
This research focuses on how aging affects physical performance and explores whether statins, commonly used for cholesterol management, can help preserve muscle strength and functional ability in older adults. The study aims to determine if statins can prevent declines in physical function that lead to disability and loss of independence. Participants will be randomly assigned to receive either statins or a placebo, allowing researchers to compare the effects on physical performance and overall health. By understanding the potential benefits and risks of statin use in this population, the research seeks to provide valuable insights for healthcare providers.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing declines in physical function or at risk of disability.
Not a fit: Patients who are not elderly or those who do not have concerns about physical performance may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic options for older adults to maintain their independence and quality of life.
How similar studies have performed: Previous research has shown promising results regarding the use of statins for various health benefits, but this specific application in preserving physical function in older adults is still being explored.
Where this research is happening
Winston-Salem, United States
- Wake Forest University Health Sciences — Winston-Salem, United States (Active)
Researchers
- Principal investigator: Houston, Denise Kathryn — Wake Forest University Health Sciences
- Study coordinator: Houston, Denise Kathryn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.