Investigating how zinc released in the brain affects hearing and cognition.
Synapse-specific effects of synaptically released zinc: implications for auditory processing
['FUNDING_OTHER'] · WEST VIRGINIA UNIVERSITY · NIH-10841619
This study is looking at how zinc in the brain affects hearing and thinking, and it's for anyone interested in understanding how problems with zinc might be linked to brain disorders.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEST VIRGINIA UNIVERSITY (nih funded) |
| Locations | 1 site (MORGANTOWN, UNITED STATES) |
| Trial ID | NIH-10841619 on ClinicalTrials.gov |
What this research studies
This research explores the role of synaptic zinc in the brain, particularly in areas related to auditory processing and cognitive function. By examining how zinc interacts with neurotransmitters during synaptic transmission, the study aims to understand its impact on neuronal signaling. Researchers will use advanced techniques such as brain slice preparations and calcium imaging to analyze these interactions in both laboratory mice and human populations. The findings could provide insights into how disruptions in zinc signaling may contribute to neurological disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with auditory processing disorders or cognitive impairments, particularly those with a family history of neurological conditions.
Not a fit: Patients with auditory processing issues not related to synaptic zinc signaling or those without cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating auditory processing disorders and cognitive impairments linked to zinc signaling.
How similar studies have performed: Previous research has indicated that zinc signaling plays a critical role in neurological function, suggesting that this approach could yield valuable insights.
Where this research is happening
MORGANTOWN, UNITED STATES
- WEST VIRGINIA UNIVERSITY — MORGANTOWN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ANDERSON, CHARLES — WEST VIRGINIA UNIVERSITY
- Study coordinator: ANDERSON, CHARLES
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.