Investigating how Zika virus infection may lead to glaucoma
Role of Zika virus (ZIKV) infection in glaucoma pathobiology
['FUNDING_R01'] · UNIVERSITY OF MISSOURI-COLUMBIA · NIH-10903977
This study is looking at how the Zika virus might lead to glaucoma in babies born to moms who had the virus, focusing on how it can affect their eye health and cause problems with pressure in the eyes.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MISSOURI-COLUMBIA (nih funded) |
| Locations | 1 site (COLUMBIA, UNITED STATES) |
| Trial ID | NIH-10903977 on ClinicalTrials.gov |
What this research studies
This research explores the connection between Zika virus infection and the development of glaucoma, particularly in infants born to infected mothers. It examines how the virus can cause increased intraocular pressure and damage to the optic nerve, leading to glaucomatous conditions. The study utilizes animal models to understand the underlying mechanisms and the potential for congenital glaucoma in newborns. By analyzing the effects of Zika virus on eye health, the research aims to uncover new insights into this emerging public health issue.
Who could benefit from this research
Good fit: Ideal candidates for this research include infants born to mothers who were infected with Zika virus during pregnancy.
Not a fit: Patients who do not have a history of Zika virus exposure or who are not infants may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for glaucoma in infants affected by Zika virus.
How similar studies have performed: While the specific link between Zika virus and glaucoma is still being explored, other studies have shown that viral infections can impact ocular health, suggesting potential for significant findings in this area.
Where this research is happening
COLUMBIA, UNITED STATES
- UNIVERSITY OF MISSOURI-COLUMBIA — COLUMBIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SINGH, PAWAN KUMAR — UNIVERSITY OF MISSOURI-COLUMBIA
- Study coordinator: SINGH, PAWAN KUMAR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.