Investigating how youth obesity and type 2 diabetes affect brain health
Understanding the Impact of Youth Onset Obesity and Type 2 Diabetes on the Neurovascular Unit
['FUNDING_R01'] · CINCINNATI CHILDRENS HOSP MED CTR · NIH-11015904
This study is looking at how type 2 diabetes in young people affects their brain health and thinking skills by comparing them to other teens who are either obese or at a healthy weight.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CINCINNATI CHILDRENS HOSP MED CTR (nih funded) |
| Locations | 1 site (CINCINNATI, UNITED STATES) |
| Trial ID | NIH-11015904 on ClinicalTrials.gov |
What this research studies
This research explores the impact of youth-onset type 2 diabetes (T2D) on brain structure and function, particularly focusing on the neurovascular unit, which is crucial for brain health. The study compares adolescents with T2D to their obese and lean peers to identify differences in brain gray matter volume and cognitive abilities. By using advanced imaging techniques, researchers aim to uncover how T2D may lead to cerebrovascular impairment and cognitive decline. The goal is to better understand the relationship between obesity, diabetes, and brain health in young individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged under 21 who have been diagnosed with type 2 diabetes or are obese without diabetes.
Not a fit: Patients who are not adolescents or do not have obesity or type 2 diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of brain health in adolescents with type 2 diabetes and obesity.
How similar studies have performed: Previous research has shown promising results in understanding the effects of obesity and diabetes on brain health, indicating that this approach has potential for significant findings.
Where this research is happening
CINCINNATI, UNITED STATES
- CINCINNATI CHILDRENS HOSP MED CTR — CINCINNATI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHAH, AMY SANGHAVI — CINCINNATI CHILDRENS HOSP MED CTR
- Study coordinator: SHAH, AMY SANGHAVI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: adult onset diabetes, Adult-Onset Diabetes Mellitus