Investigating how where you live affects prostate cancer outcomes for black men
Official title: Examining the Relationship between Residential History at Midlife and Prostate Cancer Outcomes
Funded at Research Inst of Fox Chase Can Ctr · NIH-11036306 · Data updated 2026-11-12
This study is looking at how where you live during your middle years can affect prostate cancer outcomes, especially for black men, by exploring how things like neighborhood poverty and changes in the community impact cancer treatment and survival.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Inst of Fox Chase Can Ctr NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | August 16, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $512,007 |
| NIH project number | 5R01MD018146-03 |
| Project ID | NIH-11036306 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are black men diagnosed with prostate cancer who have lived in Southeastern Pennsylvania during midlife.
✕Less likely to help
Patients who do not have a history of prostate cancer or who do not reside in the targeted geographic area may not benefit from this research.
What this research studies
This research examines the impact of residential history during midlife on prostate cancer outcomes, particularly focusing on black men who experience significant disparities in mortality rates. By linking cancer registry data with hospital billing records and historical address data, the study aims to uncover how neighborhood factors such as poverty, redlining, and gentrification influence cancer progression and survival. The research will analyze data from approximately 20,000 patients in Southeastern Pennsylvania to identify critical relationships between living environments and cancer care outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and interventions to reduce prostate cancer disparities among black men.
How similar studies have gone: Previous research has indicated that neighborhood factors can significantly impact health outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Research Inst of Fox Chase Can Ctr
Philadelphia, United States Active
Researchers
- Principal investigator: Zeigler-Johnson, Charnita M. — Research Inst of Fox Chase Can Ctr
- Study coordinator: Zeigler-Johnson, Charnita M.
Related research
Other NIH-funded projects on the same topics.
-
Cardiovascular risk planning and reduction for men with prostate cancer
A program to better predict and reduce heart disease risk in men treated for prostate cancer, especially older patients.
-
Effects of ADT on motivation and emotion in prostate cancer patients
This project looks at how androgen deprivation therapy may affect motivation and mood over time in men with prostate cancer.
-
Causal Protein Markers to Understand and Predict Prostate Cancer Risk in Africans and Europeans
A cancer research project looking at proteins linked to prostate cancer to better understand why it happens and how risk differs between African and European populations.
-
Ethical multimodal AI platform to improve prostate cancer detection with ultrasound
A patient-friendly AI system uses ultrasound and MRI information to help doctors better find prostate cancer, aiming to improve accuracy and access.
-
Characterizing epigenetic targets in prostate cancer to help AR-driven cancer
A research project at MD Anderson aims to understand how epigenetic factors shape androgen receptor signaling in prostate cancer to find new ways to treat resistant forms of the disease.
-
AR and RNA-binding in prostate cancer resistance
A cancer research grant exploring how the androgen receptor’s interaction with RNA may drive treatment resistance in prostate cancer, with potential to guide new therapies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.