Investigating how vitamin D affects lung development and chronic lung disease in infants
Role of Vitamin D in Lung Development and Bronchopulmonary Dysplasia
This study is looking at how vitamin D might help improve lung development in premature babies and protect them from a lung condition called bronchopulmonary dysplasia (BPD), using mouse models to learn more about how it works.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10765733 on NIH RePORTER |
What this research studies
This research focuses on bronchopulmonary dysplasia (BPD), a chronic lung disease that affects preterm infants and can lead to long-term respiratory issues. The study aims to understand the role of vitamin D in promoting lung development and its potential protective effects against BPD. By utilizing mouse models, the research will explore the mechanisms through which vitamin D influences lung growth and vascular development. The principal investigator, a neonatologist, seeks to enhance their skills in genetics and bioinformatics to better analyze the impact of vitamin D on lung health.
Who could benefit from this research
Good fit: Ideal candidates for this research are preterm infants who are at risk of developing bronchopulmonary dysplasia.
Not a fit: Patients who are full-term infants or those without a history of respiratory complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for preventing or mitigating chronic lung disease in preterm infants.
How similar studies have performed: Previous studies have shown promising results regarding the role of vitamin D in lung development, suggesting that this approach may lead to significant advancements in treatment.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Mandell, Erica Wynne — University of Colorado Denver
- Study coordinator: Mandell, Erica Wynne
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.