Investigating how virus genetics and host immunity affect outcomes of infections like COVID-19 and Ebola.
Project 2
This study is looking at how the genes of viruses like Lassa, Ebola, and SARS-CoV-2 affect how our immune system responds, with the goal of finding better treatments and vaccines to help patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Scripps Research Institute, the NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11010830 on NIH RePORTER |
What this research studies
This research explores the relationship between the genetics of viruses such as Lassa, Ebola, and SARS-CoV-2 and the immune responses of the host. By analyzing viral genetic variations and how they interact with the immune system, the project aims to understand factors that influence disease severity and survival rates. Patients may benefit from insights gained through advanced techniques like viral sequencing and single-cell analysis, which could lead to improved treatments and vaccines. The research will also integrate demographic and environmental data to provide a comprehensive view of the epidemiology of these infections.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been infected with or vaccinated against Lassa virus, Ebola virus, or SARS-CoV-2.
Not a fit: Patients who have not been exposed to these viruses or who are not in regions affected by these infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for patients infected with Lassa virus, Ebola virus, and SARS-CoV-2.
How similar studies have performed: Previous research has shown success in understanding viral genetics and host immunity, making this approach promising for uncovering new insights.
Where this research is happening
La Jolla, United States
- Scripps Research Institute, the — La Jolla, United States (Active)
Researchers
- Principal investigator: Andersen, Kristian Graugaard — Scripps Research Institute, the
- Study coordinator: Andersen, Kristian Graugaard
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.