Investigating how viral proteins affect the spread of cytomegalovirus and congenital infection.
The role of viral chemokines for CMV dissemination and congenital infection
This study is looking at ways to stop congenital cytomegalovirus (cCMV), a virus that can cause serious problems for babies, by targeting certain proteins that help the virus spread, with the hope of finding new ways to protect pregnant people and their babies from this infection.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10874239 on NIH RePORTER |
What this research studies
This research focuses on understanding congenital cytomegalovirus (cCMV) infection, which is a leading cause of congenital defects. The project aims to explore a novel approach to prevent cCMV by targeting specific viral chemokine-like proteins that are essential for the virus's ability to spread and infect the fetus. By studying the role of these proteins in the infection process, the researchers hope to develop strategies that could block the virus's transmission to pregnant individuals and their unborn children. The research involves both laboratory studies and potential therapeutic development.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant individuals or those planning to become pregnant who may be at risk for cytomegalovirus infection.
Not a fit: Patients who are not pregnant or do not plan to become pregnant may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new methods for preventing congenital infections caused by cytomegalovirus, ultimately reducing the incidence of birth defects.
How similar studies have performed: While there have been various approaches to CMV prevention, targeting viral chemokine-like proteins represents a novel strategy that has not been extensively tested in this context.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Fruh, Klaus J — Weill Medical Coll of Cornell Univ
- Study coordinator: Fruh, Klaus J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.