Investigating how viral exposure and age affect Alzheimer's disease progression
The Role of Viral Exposure and Age in Alzheimer's Disease Progression
This study is looking at how viral infections might affect the progression of Alzheimer's disease in older adults, especially those who are genetically at risk, to help find new ways to treat the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-11080977 on NIH RePORTER |
What this research studies
This research explores the relationship between viral infections and the progression of Alzheimer's disease (AD) in older adults. It aims to understand how repeated exposure to pathogens may contribute to the development of AD, particularly in individuals with genetic risk factors. The study will examine the effects of age on this relationship and how infections might alter cellular metabolism, potentially accelerating cognitive decline. By using animal models, researchers will gather insights that could lead to new treatment strategies for AD.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, especially those with a family history of Alzheimer's disease or other risk factors for cognitive decline.
Not a fit: Patients who are not elderly or do not have any risk factors for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential new treatments for Alzheimer's disease, particularly for those at higher risk due to age or genetic factors.
How similar studies have performed: Other research has suggested that infections may play a role in cognitive decline, indicating that this approach has potential but is still being explored.
Where this research is happening
New Orleans, United States
- Tulane University of Louisiana — New Orleans, United States (Active)
Researchers
- Principal investigator: Zwezdaryk, Kevin John — Tulane University of Louisiana
- Study coordinator: Zwezdaryk, Kevin John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.