Investigating how variations in lipid metabolism affect cancer spread
Cancer Biology Research Test-Bed Unit 2: Effects of cell-intrinsic and cell-extrinsic variations in lipid metabolism on metastasis patterns
This study is looking at how the way cancer cells use fats affects how melanoma spreads in the body, and it hopes to find new ways to help patients by understanding how certain fats can protect these cells from damage.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10903859 on NIH RePORTER |
What this research studies
This research explores how differences in lipid metabolism within cancer cells and their environment influence the patterns of metastasis in melanoma. By examining the role of oxidative stress and the protective effects of certain fatty acids, the study aims to understand why some cancer cells survive and spread more effectively than others. Patients may benefit from insights that could lead to new therapeutic strategies targeting lipid metabolism and oxidative stress in cancer treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with melanoma, particularly those experiencing metastasis.
Not a fit: Patients with non-melanoma cancers or those who are not currently undergoing treatment for cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that improve survival rates for patients with metastatic melanoma.
How similar studies have performed: Previous research has indicated that targeting oxidative stress and lipid metabolism may improve outcomes in cancer treatment, suggesting a promising avenue for further exploration.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Morrison, Sean J — Ut Southwestern Medical Center
- Study coordinator: Morrison, Sean J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.